Econic Biosciences
Econic
Econic
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Turning ecDNA from
cancer’s driver to target.

We disrupt extrachromosomal DNA to power
the next wave of cancer treatments.

Turning ecDNA from cancer’s driver to target.

We disrupt extrachromosomal DNA to power the next wave of cancer treatments.

Econic Biosciences is pioneering new ways to eradicate cancer by targeting a largely unexplored oncogenic driver.

Extrachromosomal DNA is a little-known but widespread driver of oncogenic DNA amplification, which contributes to cancer’s evolution in unprecedented ways. Econic Biosciences is building on novel mechanistic insights to develop specific approaches to therapeutically target ecDNA with the goal of improving treatment for individuals with cancer.

Concept Studies
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 Econic
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A new class
of cancer therapy
begins with
ecDNA.

A new class
of cancer therapy
begins with
ecDNA.

Two therapeutic platforms translate ecDNA vulnerabilities into selective treatments

1Heterobifunctional Molecules
Heterobifunctional molecules: protein amplified on ecDNA linked to ecDNA-specific targetsProtein amplified on ecDNAecDNA-specific Targets
Heterobifunctional molecules: protein amplified on ecDNA linked to ecDNA-specific targets
Protein amplified on ecDNAecDNA-specific Targets
2Antibody conjugates
Antibody conjugates: antibody against surface protein amplified on ecDNA, with linker to ecDNA-specific targetsSurface Protein amplified on ecDNAecDNA-specific Targets
Antibody conjugates: antibody against surface protein amplified on ecDNA, with linker to ecDNA-specific targets
Surface Protein amplified on ecDNAecDNA-specific Targets
Increased therapeutic window
Normal cells: survival. ecDNA tumor cells: cell death.
Normal cells: survival.ecDNA tumor cells: cell death.

Our Team
of experts

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Interested in
joining us?

At Econic Biosciences, we are working together with one focus in mind targeting the most powerful cause of oncogene amplification. We are looking to hire across all levels at our new headquarters in London. Join our team to help shape the future of ecDNA therapeutics.

Get in contact